Associate Scientist

About the role

AbbVie’s Immunology R&D organization is expanding its early discovery team at the Cambridge Research Center in Cambridge, MA. We are seeking a highly motivated Associate Scientist to join our Respiratory Discovery team and contribute to the identification and validation of novel therapeutics for inflammatory lung diseases.

The Cambridge-based early discovery team integrates human disease transcriptomic and multi-omic data sets with mechanistic in vitro studies to elucidate disease-driving pathways and advance innovative therapeutic strategies. The successful candidate will play a key role in providing support for the implementation and optimization of complex human cell culture systems for the development of cellular assays.

Responsibilities

• Sterile cell culture (cell lines and primary cells)
• Establish, maintain and characterize primary human and immortalized culture systems relevant to respiratory disease biology, including epithelial cells, fibroblasts and immune cell populations
• Support the generation of complex in vitro cellular models
• Execute mechanistic cellular assays to investigate pathways involved in airway inflammation and tissue remodeling

Preferred techniques

• Flow cytometry
• PCR/gene analysis
• Protein/cytokine measures via ELISA/MSD
• Western blotting
• Methods applicable to other lung-related endpoints

• Analyze data and present work in internal meetings
• Maintain detailed experimental records and ensure compliance with electronic laboratory notebook

Qualifications

• Bachelor’s Degree, or equivalent education
• Theoretical and practical knowledge to carry out job function

AbbVie competencies

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance
• Learns fast, grasps the essence and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others and nurtures innovation to make possibilities real