Associate Scientist

About the Role

AbbVie's Immunology R&D organization is expanding its early discovery team at the Cambridge Research Center in Cambridge, MA. The Cambridge-based early discovery team integrates human disease transcriptomic and multi-omic data sets with mechanistic in vitro studies to elucidate disease-driving pathways and advance innovative therapeutic strategies. The successful candidate will play a key role in providing support for the implementation and optimization of complex human cell culture systems for the development of cellular assays. The ideal candidate is scientifically curious, collaborative, enthusiastic, skilled, and dedicated, demonstrating a commitment to scientific rigor and teamwork within a fast-paced drug discovery environment.

Responsibilities

• Sterile cell culture (cell lines and primary cells)
• Establish, maintain and characterize primary human and immortalized culture systems relevant to respiratory disease biology, including epithelial cells, fibroblasts and immune cell populations
• Support the generation of complex in vitro cellular models
• Execute mechanistic cellular assays to investigate pathways involved in airway inflammation and tissue remodeling
• Analyze data and present work in internal meetings
• Maintain detailed experimental records and ensure compliance with electronic laboratory notebook

Qualifications

• Bachelor's Degree, or equivalent education
• Theoretical and practical knowledge to carry out job function

Preferred Skills

• Flow cytometry
• PCR/gene analysis
• Protein/cytokine measures via ELISA/MSD
• Western blotting
• Methods applicable to other lung-related endpoints

Key Competencies

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance
• Learns fast, grasps the "essence" and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others and nurtures innovation to make possibilities real