Associate Medical Director, Clinical Science, NS TAU

About the role

Join us as an Associate Medical Director in our Neuroscience Therapeutic Area Unit in Cambridge, MA. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. We empower our people to realize their potential through life-changing work. As a vital contributor to our inspiring, bold mission, you will lead and drive strategy for clinical studies within the overall global clinical development for assigned Takeda pipeline compound(s), considering medical, scientific, regulatory, and commercial issues.

This role involves leading or joining multi-disciplinary, multi-regional matrix teams through highly complex decisions, with responsibility for development decisions that assess and integrate input from various disciplines. You will influence Neuroscience Therapeutic Area Unit senior leadership decision-making by contributing to strategic direction.

Responsibilities

• Represent Clinical Science on Study Execution and Clinical Teams, potentially serving as co-leader.
• Support the Global Project Team to align clinical team activities with global strategy; may act as Global Clinical Lead for early-stage or preclinical programs.
• Contribute to Global Project and clinical team strategy and deliverables, including Asset Strategy, Clinical Development Plan, and Clinical Protocols.
• Recommend scope, complexity, size, and influence the budget for all aspects of a study or program.
• Critically evaluate development strategy to maintain a competitive, state-of-the-art plan aligned with regulatory requirements.
• Proactively identify challenges and develop contingency plans; recommend high-impact global decisions.
• Monitor and interpret data from internal and external studies, assessing medical and scientific implications for "go/no go" decisions or development plan modifications.
• Oversee Clinical Science activities for Synopses, Protocols, and study conduct; serve as an advisor to other clinical scientists.
• Interpret study data from scientific and medical standpoints; present conclusions to management and determine impact on compound strategy.
• Responsible for medical monitoring activities, assessing protocol conduct and individual subject safety.
• Assess overall safety information for studies and compounds in conjunction with Pharmacovigilance.
• Direct interactions with key opinion leaders relevant to assigned compounds and therapeutic area.
• Provide leadership in meetings and negotiations with key opinion leaders; establish strategy for assigned compounds.
• Lead the incorporation of advice/recommendations into clinical study and program designs.
• Evaluate potential business development opportunities and conduct due diligence assessments.
• Contribute to the development and negotiation of clinical development plans for alliances or in-licensing opportunities.
• Interface with partners to achieve Takeda’s strategic goals while maintaining strong working relationships.
• Represent clinical science on internal task forces and global cross-functional teams.
• Mentor, motivate, empower, develop, and retain staff to support assigned activities.

Qualifications

• MD, MD/PhD, or internationally recognized equivalent.
• 3+ years of clinical research experience within the pharmaceutical industry, CRO, health-related consulting, or academia.
• Previous experience successfully leading matrix teams preferred.
• Experience in designing and executing first-in-human and early proof-of-concept trials preferred.

Skills

• Superior communication, strategic, interpersonal, and negotiating skills.
• Ability to proactively predict issues and solve problems.
• Ability to drive decision-making within multi-disciplinary, multi-regional matrix teams.
• Diplomacy and positive influencing abilities.
• Neurology therapeutic area knowledge preferred; specialization in Neurology or subspecialty expertise in neuromuscular or neurodegenerative disease preferred.
• Knowledge of regional/global regulatory requirements and GCP/ICH guidelines.

Schedule

This position is classified as "hybrid" in accordance with Takeda’s Hybrid and Remote Work policy. Ability to travel approximately 10–20%, including overnight and some international trips.

Pay

U.S. Base Salary Range: $198,500.00 – $311,850.00. The actual base salary offered may depend on qualifications, experience, skills, education, location, and other factors. U.S.-based employees may also be eligible for short-term and long-term incentives.

Benefits

• Medical, dental, and vision insurance.
• 401(k) plan with company match.
• Short-term and long-term disability coverage.
• Basic life insurance.
• Tuition reimbursement program.
• Paid volunteer time off and company holidays.
• Well-being benefits.
• Up to 80 hours of sick time per calendar year.
• New hires eligible to accrue up to 120 hours of paid vacation per year.