Associate Director Translational Pharmacokinetics and Pharmacokinetic/Pharmacodynamic

Responsibilities

• Serving as a subject matter expert on Preclinical PK/PD within Discovery-stage project teams and guiding the design of preclinical PK/pharmacology studies.
• Collaborating with various internal groups such as Therapeutic Proteins, Therapeutic Function Areas, Assay Development, Precision Medicine, Preclinical Operations, and PPK/PD management to develop and execute PK strategies for projects.
• Effectively communicating project team queries, expectations, and timelines to management.
• Conducting and reporting PK/PD analyses based on data from preclinical studies.
• Working closely with Toxicology, Pathology, Clinical Pharmacology, and Quantitative Pharmacology teams within the Drug Safety and Pharmacometrics department to deliver data and regulatory documents supporting project progression.

Requirements

• PhD in Pharmacology, Pharmacokinetics, Biology/Molecular Biology, or Biochemistry with more than 8 to 10 years of relevant experience in biotech or pharma.
• Deep theoretical and applied understanding of PK and PD to interpret the pharmacology and biology of therapeutic proteins. Experience with other modalities such as siRNA, CRISPR-based therapeutics, and cell therapies is highly beneficial.
• Proven ability to plan, coordinate, lead PK and/or PK/PD studies, and analyze related data.
• Familiarity with PK/PD (e.g., WinNonLin), data visualization and AI software and experience writing scientific reports and regulatory summaries.

Qualifications

• Thrive in a fast-paced, collaborative environment.
• Passionate about science and motivated to contribute to bringing new drugs to patients.
• Desire exposure to multiple therapeutic areas and emerging modalities.
• Excellent written and verbal communication, presentation, influencing, and leadership skills.