Associate Director Medical Affairs, Endocrine Medical Sciences

Ascendis Pharma is a dynamic, fast-growing global biopharmaceutical company with locations in Denmark, Europe, and the United States, advancing programs in Endocrinology Rare Disease and Oncology. Guided by core values of Patients, Science, and Passion, the company uses its TransCon® drug development platform to develop potentially best-in-class therapies addressing unmet medical needs. This role joins the Endocrine Medical Sciences team for the US business, reporting to the US Medical Director, and supports management and implementation of phase 4 studies and registries, pre-launch, launch, and post-launch activities, and medical review of promotional materials for marketed product(s). The position requires expertise in endocrine and rare disorders, with a focus on growth-related disorders and/or hypoparathyroidism for Ascendis TransCon Program(s). The candidate must have availability to work in Princeton, NJ on a weekly basis (three days per week on-site).

Responsibilities

• Serve as the medical/scientific reviewer of promotional assets for assigned product(s), and collaborate with Commercial, Legal, and Regulatory for development and review of Labeling, advertising, and promotional materials, providing evidence-based input to support cross-functional decisions on claims, messaging, and scientific accuracy.
• Ensure materials are medically accurate, including that claims are appropriately supported by evidence, references are correctly cited, and the overall impression is fair and not misleading.
• Verify that statements in promotional materials are consistent with the approved indication/label.
• Cross-check everything against underlying clinical data, literature, abstracts/manuscripts and ensure summary data are accurate and in context.
• Provide ongoing therapeutic area, product, and competitive intelligence knowledge to the team to maintain up-to-date scientific accuracy.
• Build and manage relationships and strategic partnerships, and interact regularly with Key Opinion Leaders/Influencers, clinical investigators, healthcare customers, strategic alliance partners, vendors, professional societies and organizations, and patient advocacy groups, synthesizing external insights to inform internal cross-functional discussions and decision-making.
• Work with internal stakeholders including Commercial, Legal, Regulatory, Clinical Development, Clinical Operations, Compliance, Pharmacovigilance, Biometrics, Global Communications, and other functional group contributors to support the US Medical Director in successful management of Medical Affairs projects, providing medical perspective and scientific guidance within cross-functional discussions.
• Support the US Medical Director in the design and implementation of medical strategies and tactical plans while providing thought leadership for medical publication planning, medical education, and medical information system development, including contributing data-driven medical insight to inform strategic direction and execution decisions.
• Serve as a scientific expert for Medical Affairs projects within the designated TransCon Program(s).
• Support the US Medical Director in the development of strategic imperatives and tactical medical plans to enhance healthcare practitioner education to improve patient outcomes.
• Support the Medical Affairs team and the US Medical Director in design and conducting post-marketing studies and medical materials review.
• Support the development, management, and execution of US Medical Advisory Boards.
• Develop and deliver presentations on MA projects to both internal and external audiences within legal, compliance, and regulatory guidelines.
• Represent Ascendis Medical Affairs internally and externally.
• Stay abreast of up-to-date knowledge on all clinical data relevant to TransCon programs, competitive landscape, new therapies, clinical trends, and newly issued regulatory rules and FDA guidance to promptly identify any potential impact on existing medical programs or strategies, competitive environment, or changes to product programs.
• Contribute medical and scientific perspectives within cross-functional teams, supporting evidence-based decision-making across Medical Affairs activities.

Requirements

• PharmD/PhD with at least 5–8 years of total work experience, including a minimum of 3 years’ industry experience in medical affairs in a relevant therapeutic area and experience in medical promotional review.
• Substantial knowledge/experience with rare endocrine disorder or (non-Oncology related) rare diseases (preferred).
• Strong record of scientific and clinical inquiry.
• Demonstrated leadership and team building skills as well as the ability to perform effectively in a dynamic environment.
• Flexibility to adapt culturally.
• Demonstrated strategic and critical thinking.
• Excellent communication skills (oral and written) and proven organizational skills.
• The ability to lead directly and indirectly by influence, including strong problem solving, conflict resolution, and analysis.
• Ability to work on-site in Princeton three days per week.

Pay

The estimated salary range for this position is $190,000 – $210,000. Actual salary determination depends on factors including experience, qualifications, and geographic location. This position may be eligible for a discretionary annual bonus or an incentive compensation plan (eligibility varies based on role and position level), discretionary stock-based long-term incentives, and paid time off.

Benefits

• 401(k) plan with company match
• Medical, dental, and vision plans
• Company-offered Life and Accidental Death & Dismemberment (AD&D) insurance
• Company-provided short and long-term disability benefits
• Pet Insurance and Legal Insurance
• Employee Assistance Program
• Employee Discounts
• Professional Development
• Health Savings Account (HSA)
• Flexible Spending Accounts
• Various incentive compensation plans
• Accident, Critical Illness, and Hospital Indemnity Insurance
• Mental Health resources
• Paid leave benefits for new parents