Jobs · Management · New Jersey

Associate Director - Computer Systems Validation

Celltrion Inc · Branchburg, NJ · 2 wk ago
On-siteManagement$135k–$180k/yrFull-time

Brand Description

The leader of Computer System Validation and Computer Software Assurance (CSV/CSA) is responsible for leading and governing all site-wide CSV and CSA activities to ensure that computerized systems are validated, compliant, and maintained in accordance with GMP regulations, 21 CFR Part 11, and global quality standards.

Key Objectives/Deliverables

  • Manage for Results / Strategic Planning: Lead and develop a high performing, site-wide CSV/CSA team responsible for validation execution, inclusive of resource planning, skill building, training, and inspection readiness.

  • Define and maintain the site-wide CSV/CSA strategy for information technology (IT) and operational technology (OT) policies and procedures aligned with site, global, and regulatory expectations.

  • Maintain and implement an annual technical continuous improvement and asset qualification monitoring (AQM) agenda.

  • Oversee execution of validation activities across all GMP systems, including: supporting risk assessments based on system criticality and data impact, validation planning and test execution (IQ/OQ/PQ), and traceability / documentation completeness.

  • Ensure all computerized systems remain in a validated state throughout their lifecycle.

  • Partner with QA to maintain compliance with data integrity, audit trail, and security requirements consistent with regulatory expectations (GAMP 5, EU Annex 11, 21 CFR Part 11, etc.).

  • Lead regulatory inspection readiness for CSV/CSA and support inspection activities.

  • Ensure effective handover between project and operational phases of computerized systems.

  • Influence internal and external customers/regulators/partners, including to adopt a different point of view on difficult concepts.

  • Partner with key stakeholders to harmonize validation approaches and incorporate regulatory feedback.

  • Benchmark through industry consortia and conferences.

  • Provide representation where required for cross-functional and cross-site technical initiatives.

Basic Requirements

  • Experience performing qualification of manufacturing automated equipment and computerized systems.

  • Understanding of FDA and EU regulations and guidelines and knowledgeable of current industry trends.

  • Organizational and time management skills that will allow for effective prioritization of activities.

  • Understanding of key data integrity principles to ensure requirements are aligned to appropriate testing strategies with the use of electronic data / databases.

  • Broad knowledge of computer systems and automated process equipment or utility systems, such as Rockwell (PLC/HMI), MES, ERP, and OSI PI.

  • Strong communication skills, both oral and written to effectively communicate technical information in a clear and concise manner within a GMP environment.

  • Strong analytical, problem solving, and excellent interpersonal skills.

Additional Preferences

  • Prior leadership experience preferred.

Education Requirements

  • Bachelor’s degree in engineering, science, or related discipline with a minimum of 5 years’ experience in cGMP biopharmaceutical manufacturing.

Pay

$135,000 - $180,000

Schedule

This is a banded role, and candidates will be placed within the range based on experience, skills, internal equity, and market considerations.

Benefits

  • Paid time off (holidays, vacation, and additional leave)

  • Medical, dental, and vision insurance

  • Life insurance

  • A company-matched retirement savings plan

  • Wellness programs

  • Short- and long-term disability benefits

Qualifications

  • Up to 10% travel

  • On-call availability

  • May involve shift work

  • Hybrid work flexibility may be available based on business needs

  • No relocation assistance provided

Skills

  • Leadership

  • Quality Assurance

  • Data Integrity

  • Computer Systems Validation

  • Regulatory Compliance

  • Collaboration

  • Project Management

  • Technical Writing

Benefits

  • Comprehensive benefits package

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