Associate Director, Commercial Supply Chain Management & Planning
About the role
The Stoke Therapeutics team is seeking an experienced and driven Associate Director, Commercial Supply Chain Management and Planning to lead the planning, forecasting, and execution of commercial supply strategies that ensure uninterrupted drug availability. This individual partners cross-functionally with Commercial Operations, Quality, Regulatory, Manufacturing, and external vendors to drive demand and supply planning, launch supply plans, and cold-chain logistics to help build and scale the function. The role plays a critical part in leading commercial supply chain activities from launch through steady-state operations, including artwork development, CMO timeline management, and DSCSA / Serialization compliance, while also supporting demand planning and ERP setup and design. The ideal candidate possesses strong expertise in commercial supply management, forecasting, inventory planning, ERP systems, and cross-functional collaboration, with excellent communication, organizational, and problem-solving skills. Stoke is located in Bedford, MA, and will be moving to a new location in Waltham, MA by the end of 2026. This position is a lab-based position currently in the Bedford office and will later be based in Waltham. Travel: This position will require approximately 5% travel.
Responsibilities
- Lead the execution of the commercial supply chain strategy, helping build capability from initial launch into a scalable operating model.
- Lead supply chain coordination of commercial artwork management and secondary packaging workstream.
- Own day – to – day demand and supply planning activities and support the implementation and facilitation of the S&OP process.
- Ensure compliance with GxP, DSCSA/serialization, and applicable global regulatory requirements across the distribution network.
- Develop launch supply plans in collaboration with CMC, QA, RA, and Commercial Operations.
- Drive supply planning for both clinical and commercial supply chains.
- Support the execution of cold-chain logistics, including temperature integrity and chain of custody.
- Partner with Quality to support GxP compliance, including change controls, continuous improvement, and deviation handling.
- Track and manage timelines for internal activities and external CMO production activities to support continuous supply of commercial materials.
- Support development of Commercial Supply Chain SOPs for inspection readiness and GxP compliance.
- Serve as a supply chain representative in ERP setup, configuration, and design decisions.