Jobs · Information Technology · Massachusetts

Associate Computational Biologist

Dana-Farber Cancer Institute · Boston, MA · 1 mo ago
Information Technology$60k–$67k/yrFull-time

About the role

The Associate Computational Biologist is training to become a Computational Biologist. They are responsible for routine data analysis or processing of biological data, with a focus on high-throughput technologies and genomic databases, under the supervision of mentor. The Computational Biologist is a quantitative scientist who collaborates with scientific investigators and with other research staff in the analysis of high-throughput data, and dissemination of scientific results. The Computational Biologist may work on many types of projects and areas of research including cancer genomics, functional genomics, immuno-oncology, molecular imaging, data management and integration, and querying biological databases.

Responsibilities

  • Data Processing: Builds data processing pipelines to convert raw data into formats compatible with conventional statistical analysis and visualization under supervision of mentor
  • Data Analysis: Follows a detailed manual to perform routine
  • Data and Software Management: Monitors, downloads, organizes, and manages data from public data repositories or generated by collaborators
  • Manuscript Preparation: Helps prepare tables and figures
  • Research Portfolio Management: Trains to develop timelines and components for multiple routine projects; masters multi-tasking so that complex projects involving many interdisciplinary individuals move forward smoothly
  • Works with postdoctoral mentor Priyanka Sharma to complete ribosome profiling analysis from start to final graphs. This will include building genotype-specific RNA expression maps that include aberrant RNA species (ptRNAs and ERV RNAs) and predicting novel open reading frames for interpretation of immunopeptidomic data.
  • Collaborate with Priyanka to expedite analysis of direct RNA long-read sequencing data for gene expression and RNA modifications, with the goal of this reaching submission February 2027.
  • Complete single cell RNA sequencing pipelines for mutant and wild-type CDK13 patient samples. Help Megan to identify the correct controls for the literature and take ownership over this part of the project.

Qualifications

  • Minimum Job Qualifications: Bachelor's degree in a STEM field, with no prior experience necessary.

Skills

  • Knowledge of UNIX/Linux
  • Familiarity with scripting in Python and statistical programming using R
  • Familiarity with principles of experimental design and the modern data analysis paradigms
  • Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight
  • Strong interpersonal skills – ability to effectively interact with all levels of staff and external contacts
  • Excellent analytical, organizational and time management skills

Pay

$60,000.00 - $67,466.00 per year

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