Advisor/Sr. Advisor Formulation Development

About the Role

At Lilly, we unite caring with discovery to help make life better for people around the world. The Lilly Bioproduct Research and Development (BR&D) organization is focused on the development and commercialization of parenteral formulations of small molecules and large molecules such as monoclonal antibodies, novel therapeutic proteins, and peptides. The organization is also committed to the development of genetic medicines, including active investments in Oligonucleotide development, nanomedicines for tissue-specific targeting, and other gene delivery strategies. The drug product team is investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates, and AAV and other non-viral vector delivery.

We are seeking a highly motivated Scientist with an interest or experience in developing parenteral drug product through various stages of clinical development. If you are interested in building platforms for new and novel therapeutic modalities and exploring new frontiers in formulation and drug delivery strategies, consider joining our diverse team.

Responsibilities

• Represent the Drug Product team in CM&C teams and support the formulation and process development of protein, peptide, oligonucleotides, and other novel modalities in clinical development.
• Perform hands-on experimental activities in the formulation group to support clinical development of parenteral drug products and other complex formulations.
• Build process capabilities for lab scale, early phase clinical scale, and scale-up technologies for parenteral drug product and other complex formulations.
• Support tech transfer of process and formulation to clinical manufacturing sites.
• Work closely with synthetic chemistry, toxicology, ADME groups, analytical teams, and device teams to develop stable and patient-centric drug products.
• Support monoclonal antibody, protein, and peptide programs in various stages of development.
• Provide technical support in the areas of formulation and drug delivery.
• Partner with key teams such as discovery, drug product delivery, and device to develop innovative, patient-focused solutions in an integrated fashion.
• Collaborate with Discovery teams on establishing systems for seamless handoff of assets from discovery to clinical development.
• Innovate or assess cutting-edge formulation methodologies for complex or unstable bioproducts (peptides, proteins, fusion proteins, and drug conjugates).
• Identify and spearhead research efforts on understanding new drug delivery technologies in targeted drug delivery and other novel fields, and establish proof of concept for technologies under development.
• Establish and leverage strategic relationships with academia and start-ups to accelerate and access emerging innovation.
• Drive a strong innovation agenda for the team, leading to publications, presentations, and industry-wide influence.
• Wear multiple functional hats to manage input into various complementary parts of the project in a rapid and localized manner.

Requirements

• Earned Bachelor’s degree or Master’s degree in Pharmaceutics, Pharmaceutical Sciences, Biochemistry, Chemical Engineering, or a related field.
• 10+ years of pharmaceutical or biotech industry experience.
• Prior experience developing processes and understanding basic principles and analytical techniques necessary to characterize large molecules or biological materials.
• Knowledge and understanding of parenteral drug formulation development, parenteral manufacturing and aseptic technologies, and/or drug product process development.
• Ability and desire to communicate and work cross-functionally within the team and with other teams consistently.

Qualifications (Preferred)

• Earned PhD in a relevant field with up to 5 years of industry experience.
• Background encompassing both innovation and technical development of oligos, protein, peptide, viral, or cell therapeutics, as evidenced by a history of publications.
• Knowledge and hands-on experience with lab automation and high-throughput formulation screening.

Additional Information

Location: Indianapolis, IN. This position requires in-office/lab attendance daily and does not allow for hybrid/remote work. The work environment is primarily in a laboratory.

Pay

The anticipated wage for this position is $151,500 - $244,200. Full-time equivalent employees are also eligible for a company bonus (depending on company and individual performance).

Benefits

• Comprehensive benefit program, including eligibility to participate in a company-sponsored 401(k) and pension.
• Vacation benefits.
• Eligibility for medical, dental, vision, and prescription drug benefits.
• Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts).
• Life insurance and death benefits.
• Certain time off and leave of absence benefits.
• Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).