Advisor, Bioanalytical Chemistry
Eli Lilly and Company · Watertown, MA · 1 mo ago
OTHR$168k–$268k/yrFull-time
We need to output HTML fragment with headings for sections: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Only include sections that have real specific content. Let's parse posting.
Content includes:
- Intro about Lilly and Orna Therapeutics: description of company, mission. Could be "About the role"? Actually "About the role" maybe includes description of role and company. We'll put a section About the role with description.
- Responsibilities: list bullet points under "Key Responsibilities". We'll put
for sections: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Only include sections that have real specific content. Let's parse posting.
Content includes:
- Intro about Lilly and Orna Therapeutics: description of company, mission. Could be "About the role"? Actually "About the role" maybe includes description of role and company. We'll put a section About the role with description.
- Responsibilities: list bullet points under "Key Responsibilities". We'll put Responsibilities
with - each bullet.
- Basic Qualifications: Ph.D. ... with 3+ years experience. That's qualifications. Could be under Requirements or Qualifications. We'll treat as Requirements (or Qualifications). The instruction: Use headings for sections like About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. We need to decide which to use. We have qualifications (Ph.D., experience). Also Additional Skills/Preferences: hands-on expertise etc. That's Skills.
- Benefits: described later: comprehensive benefit program, list items. Also mention bonus. So Benefits section.
- Pay: "Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $168,000 - $268,400". That's pay info. So Pay section.
- Schedule: Not mentioned explicitly. There's "Full-time equivalent employees also will be eligible for a company bonus". Implies full-time. But schedule not given. We should not create Schedule section unless posting actually states them. It does not state schedule explicitly, so we omit Schedule.
- Also there is EEO boilerplate etc which we must remove.
- Also mention "Lilly is dedicated to helping individuals with disabilities..." that's EEO/accommodation; remove.
- Also mention employee resource groups; that's maybe part of Benefits? Could be considered Benefits but it's more about ERGs. Might be considered Benefits? It's a benefit program. Could include under Benefits as bullet. But we already have benefits list; we could add ERGs as another bullet. However the instruction: remove EEO/equal-opportunity boilerplate. ERGs are not EEO but maybe still considered boilerplate? It's about diversity groups. Might be considered part of benefits? The posting includes them after EEO statement. It's not strictly required to keep; but it's substantive info about employee groups. I'd keep it under Benefits as a bullet.
- Also mention "Lilly reserves the right to amend..." that's legal boilerplate; remove.
- Also mention "#WeAreLilly" maybe remove as it's a tagline.
Thus sections: About the role, Responsibilities, Requirements (or Qualifications), Skills, Benefits, Pay.
We need to decide between Requirements and Qualifications. The posting has "Basic Qualifications" and "Additional Skills/Preferences". So we can have Requirements (Basic Qualifications) and Skills (Additional Skills/Preferences). Or we could have Qualifications for basic and Skills for additional. Let's follow: Requirements = Basic Qualifications. Skills = Additional Skills/Preferences.
Thus:
About the role
... description of Lilly and Orna Therapeutics, role purpose ...
Then Responsibilities list.
Then Requirements list (maybe just one item: Ph.D. ... with 3+ years experience). Could be a - .
Then Skills list (hands-on expertise etc).
Then Benefits list (comprehensive benefit program items + bonus + ERGs).
Then Pay paragraph.
We must not repeat job title as heading. No job ID.
Let's extract exact text for About the role: The first paragraph(s) up to "This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us." Then also description of Orna Therapeutics: "Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, is an innovative biotechnology startup based in Watertown, MA, committed to developing groundbreaking therapies for diseases that current approaches cannot address. With our pioneering circular RNA technology, developed at MIT, we are at the forefront of advancing the next generation of RNA therapeutics. Our pioneering expression and delivery platform positions us to tackle complex diseases, including B cell-driven autoimmune disorders, B cell malignancies, sickle cell disease, and beyond. We are seeking an experienced scientist with expertise in liquid chromatography-mass spectrometry (LC-MS/MS) to lead bioanalytical method development, validation, and sample analysis supporting pharmacokinetic (PK) and protein biomarker assessments across drug development programs. This role will contribute scientific and technical leadership to cross-functional teams supporting discovery studies, including biotherapeutics and novel modalities (e.g., LNP, RNA-based therapeutics)."
We can combine into a paragraph.
Now Responsibilities bullet points: list each line after "Key Responsibilities". Let's capture them:
- Design, develop, and qualify LC-MS/MS methods for quantifying protein/peptide biomarkers and PK analytes in biological matrices (plasma, serum, tissue) in accordance with FDA/EMA Bioanalytical Method Validation (BMV) guidance
- Lead technical strategy for immunoaffinity-LC-MS/MS (IA-LC-MS/MS) or hybrid LBA-LC-MS approaches for large-molecule and biomarker analysis
- Oversee sample analysis campaigns supporting animal studies, including troubleshooting matrix effects, parallelism, and assay robustness issues
- Author and review method validation protocols, reports, and SOPs; ensure compliance with regulatory and quality standards
- Serve as scientific point of contact for CRO partners, overseeing method transfer, technical review, and data quality
- Collaborate with discovery teams to support study design and interpretation of bioanalytical data
- Present data and technical rationale in cross-functional settings
- Mentor junior scientists and contribute to department-level technical training and process improvement
Now Requirements: "Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences or related scientific discipline with 3+ years of relevant industry experience". That's it.
Now Skills: "Additional Skills/Preferences" bullet list:
- Hands-on expertise with LC-MS/MS instrumentation (e.g., triple quadrupole, high-resolution MS) for quantitative protein/peptide bioanalysis
- Understanding of PK assay development principles and regulatory bioanalytical guidance (FDA 2018 BMV, EMA equivalents)
- Experience with large molecule/biotherapeutic bioanalysis (e.g., biomarker proteins, mAbs, fusion proteins, novel modalities)
Now Benefits: The paragraph after "Actual compensation will depend..." includes bonus and benefits. Let's extract:
- Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
- In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
- Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. (This is legal boilerplate; we should remove? It's about benefits modification; might be considered boilerplate. The instruction: remove cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate. This is legal boilerplate about benefit programs; likely remove. So we omit that sentence.
- Also employee resource groups list: "Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL)." This is substantive; we can include as bullet under Benefits.
Thus Benefits bullets:
- Company bonus (depending on company and individual performance) for full-time equivalent employees.
- Comprehensive benefit program including: company-sponsored 401(k); pension; vacation benefits; medical, dental, vision and prescription drug benefits; flexible benefits (healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; well-being benefits (employee assistance program, fitness benefits, employee clubs and activities).
- Employee resource groups (ERGs) such as AMECA, BE@Lilly, CCN, EnAble, Evolve, LIN, OLA, Pride (LGBTQ+ Allies), VLN, WILL.
Now Pay: "Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $168,000 - $268,400". We'll put as paragraph.
Now ensure we don't include any boilerplate like "Lilly is dedicated to helping individuals with disabilities..." etc.
Now output HTML fragment.
Let's craft:
About the role
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, is an innovative biotechnology startup based in Watertown, MA, committed to developing groundbreaking therapies for diseases that current approaches cannot address. With our pioneering circular RNA technology, developed at MIT, we are at the forefront of advancing the next generation of RNA therapeutics. Our pioneering expression and delivery platform positions us to tackle complex diseases, including B cell-driven autoimmune disorders, B cell malignancies, sickle cell disease, and beyond. We are seeking an experienced scientist with expertise in liquid chromatography-mass spectrometry (LC-MS/MS) to lead bioanalytical method development, validation, and sample analysis supporting pharmacokinetic (PK) and protein biomarker assessments across drug development programs. This role will contribute scientific and technical leadership to cross-functional teams supporting discovery studies, including biotherapeutics and novel modalities (e.g., LNP, RNA-based therapeutics).
Responsibilities
- Design, develop, and qualify LC-MS/MS methods for quantifying protein/peptide biomarkers and PK analytes in biological matrices (plasma, serum, tissue) in accordance with FDA/EMA Bioanalytical Method Validation (BMV) guidance
- Lead technical strategy for immunoaffinity-LC-MS/MS (IA-LC-MS/MS) or hybrid LBA-LC-MS approaches for large-molecule and biomarker analysis
- Oversee sample analysis campaigns supporting animal studies, including troubleshooting matrix effects, parallelism, and assay robustness issues
- Author and review method validation protocols, reports, and SOPs; ensure compliance with regulatory and quality standards
- Serve as scientific point of contact for CRO partners, overseeing method transfer, technical review, and data quality
- Collaborate with discovery teams to support study design and interpretation of bioanalytical data
- Present data and technical rationale in cross-functional settings
- Mentor junior scientists and contribute to department-level technical training and process improvement
Requirements
- Ph.D. in Analytical Chemistry, Bi
About the role
... description of Lilly and Orna Therapeutics, role purpose ...
Then Responsibilities list. Then Requirements list (maybe just one item: Ph.D. ... with 3+ years experience). Could be a- .
Then Skills list (hands-on expertise etc).
Then Benefits list (comprehensive benefit program items + bonus + ERGs).
Then Pay paragraph.
We must not repeat job title as heading. No job ID.
Let's extract exact text for About the role: The first paragraph(s) up to "This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us." Then also description of Orna Therapeutics: "Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, is an innovative biotechnology startup based in Watertown, MA, committed to developing groundbreaking therapies for diseases that current approaches cannot address. With our pioneering circular RNA technology, developed at MIT, we are at the forefront of advancing the next generation of RNA therapeutics. Our pioneering expression and delivery platform positions us to tackle complex diseases, including B cell-driven autoimmune disorders, B cell malignancies, sickle cell disease, and beyond. We are seeking an experienced scientist with expertise in liquid chromatography-mass spectrometry (LC-MS/MS) to lead bioanalytical method development, validation, and sample analysis supporting pharmacokinetic (PK) and protein biomarker assessments across drug development programs. This role will contribute scientific and technical leadership to cross-functional teams supporting discovery studies, including biotherapeutics and novel modalities (e.g., LNP, RNA-based therapeutics)."
We can combine into a paragraph.
Now Responsibilities bullet points: list each line after "Key Responsibilities". Let's capture them:
- Design, develop, and qualify LC-MS/MS methods for quantifying protein/peptide biomarkers and PK analytes in biological matrices (plasma, serum, tissue) in accordance with FDA/EMA Bioanalytical Method Validation (BMV) guidance
- Lead technical strategy for immunoaffinity-LC-MS/MS (IA-LC-MS/MS) or hybrid LBA-LC-MS approaches for large-molecule and biomarker analysis
- Oversee sample analysis campaigns supporting animal studies, including troubleshooting matrix effects, parallelism, and assay robustness issues
- Author and review method validation protocols, reports, and SOPs; ensure compliance with regulatory and quality standards
- Serve as scientific point of contact for CRO partners, overseeing method transfer, technical review, and data quality
- Collaborate with discovery teams to support study design and interpretation of bioanalytical data
- Present data and technical rationale in cross-functional settings
- Mentor junior scientists and contribute to department-level technical training and process improvement
Now Requirements: "Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences or related scientific discipline with 3+ years of relevant industry experience". That's it.
Now Skills: "Additional Skills/Preferences" bullet list:
- Hands-on expertise with LC-MS/MS instrumentation (e.g., triple quadrupole, high-resolution MS) for quantitative protein/peptide bioanalysis
- Understanding of PK assay development principles and regulatory bioanalytical guidance (FDA 2018 BMV, EMA equivalents)
- Experience with large molecule/biotherapeutic bioanalysis (e.g., biomarker proteins, mAbs, fusion proteins, novel modalities)
Now Benefits: The paragraph after "Actual compensation will depend..." includes bonus and benefits. Let's extract:
- Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
- In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
- Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. (This is legal boilerplate; we should remove? It's about benefits modification; might be considered boilerplate. The instruction: remove cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate. This is legal boilerplate about benefit programs; likely remove. So we omit that sentence.
- Also employee resource groups list: "Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL)." This is substantive; we can include as bullet under Benefits.
Thus Benefits bullets:
- Company bonus (depending on company and individual performance) for full-time equivalent employees.
- Comprehensive benefit program including: company-sponsored 401(k); pension; vacation benefits; medical, dental, vision and prescription drug benefits; flexible benefits (healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; well-being benefits (employee assistance program, fitness benefits, employee clubs and activities).
- Employee resource groups (ERGs) such as AMECA, BE@Lilly, CCN, EnAble, Evolve, LIN, OLA, Pride (LGBTQ+ Allies), VLN, WILL.
Now Pay: "Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $168,000 - $268,400". We'll put as paragraph.
Now ensure we don't include any boilerplate like "Lilly is dedicated to helping individuals with disabilities..." etc.
Now output HTML fragment.
Let's craft:
About the role
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, is an innovative biotechnology startup based in Watertown, MA, committed to developing groundbreaking therapies for diseases that current approaches cannot address. With our pioneering circular RNA technology, developed at MIT, we are at the forefront of advancing the next generation of RNA therapeutics. Our pioneering expression and delivery platform positions us to tackle complex diseases, including B cell-driven autoimmune disorders, B cell malignancies, sickle cell disease, and beyond. We are seeking an experienced scientist with expertise in liquid chromatography-mass spectrometry (LC-MS/MS) to lead bioanalytical method development, validation, and sample analysis supporting pharmacokinetic (PK) and protein biomarker assessments across drug development programs. This role will contribute scientific and technical leadership to cross-functional teams supporting discovery studies, including biotherapeutics and novel modalities (e.g., LNP, RNA-based therapeutics).
Responsibilities
- Design, develop, and qualify LC-MS/MS methods for quantifying protein/peptide biomarkers and PK analytes in biological matrices (plasma, serum, tissue) in accordance with FDA/EMA Bioanalytical Method Validation (BMV) guidance
- Lead technical strategy for immunoaffinity-LC-MS/MS (IA-LC-MS/MS) or hybrid LBA-LC-MS approaches for large-molecule and biomarker analysis
- Oversee sample analysis campaigns supporting animal studies, including troubleshooting matrix effects, parallelism, and assay robustness issues
- Author and review method validation protocols, reports, and SOPs; ensure compliance with regulatory and quality standards
- Serve as scientific point of contact for CRO partners, overseeing method transfer, technical review, and data quality
- Collaborate with discovery teams to support study design and interpretation of bioanalytical data
- Present data and technical rationale in cross-functional settings
- Mentor junior scientists and contribute to department-level technical training and process improvement
Requirements
- Ph.D. in Analytical Chemistry, Bi