2027 Future Talent Program - Protein & Structural Chemistry - Intern

About the role

The Structural Chemistry groups use X-ray crystallography and Cryo-electron microscopy to determine structures of drug/target complexes, biologics, and other relevant biological macromolecules to enable structure-based drug discovery. This is a paid internship targeted to start in June 2027 and run for 10-12 weeks.

Responsibilities

• Work to support drug discovery with structural information using some or all of the following methods: preparative protein purification, characterization using SDS-PAGE, spectroscopic and analytical chromatographic methods, biochemical and biophysical pre-crystallization assays, crystallization screening and crystal optimization, crystal harvesting, grid preparation for Cryo-EM, and data collection, processing, and structure determination and critical analysis of protein-ligand structural data
• Maintain accurate electronic notebook recording and safe laboratory practices
• Present data and interpretations to a team of scientists
• Attend departmental and team meetings to gain a wider perspective of the drug development process in the pharmaceutical industry

Required Education, Experience and Skills

• Must be pursuing a BS/BA or Master's/Ph.D. degree in a related field with demonstrated interest/experience in research areas relevant to the drug discovery process
• Must have basic laboratory skills and research experience such as: structural biology, protein biochemistry, biophysics, BioNMR, mass spectrometry, molecular biology, protein expression and purification, protein characterization using biochemical and biophysical techniques, and safe lab practices
• Must have completed at least two years of studies toward BS/BA degree or at least 1 year towards Master's/PhD at time of internship
• Must be currently enrolled in an academic program at the time of application and be continuing education for at least 1 semester once internship completes
• Must be available for full-time employment for 10-12 weeks during June - August 2027

Preferred Experience and Skills

• Significant interest in protein structure/function
• Experience with preparation of challenging biological macromolecules such as membrane proteins, or characterizing proteins using functional assays or techniques that measure ligand binding
• GPA of 3.0 or higher

Pay

The salary range for this role is $39,108 through $111,111.

Locations: Rahway, NJ; West Point, PA; Boston, MA; South San Francisco, CA

Note: If selected for an interview, applicants must be prepared to submit letters of recommendation, a brief research statement, and a copy of their transcript.