Jobs · Administrative · Massachusetts

2027 Future Talent Program – Chemical Biology Spatial Biology & Proteomics – Co-op

Merck · Cambridge, MA · 5 days ago
Administrative$39k–$111k/yrFull-time

About the role

The Future Talent Program features co-ops that last up to 6 months and will include one or more projects. These opportunities in our Research & Development Division can provide you with great development and a chance to see if we are the right company for your long-term goals. Our company's Research Lab's Chemical Biology group within Discovery Chemistry is seeking a co-op with a passion for scientific research, strong academic performance, communication skills, and the ability to work on cross-functional teams. We offer opportunities in our state-of-the-art science laboratories to solve fundamental synthetic or biological problems relevant to drug discovery and development, while functioning as a fully integrated member of the company project teams.

About Chemical Biology (Cambridge, MA)

Our Company's Chemical Biology (comprising of chemistry, proteomics, and cell pharmacology) focuses on providing novel, high-quality targets and expanding confidence on molecular mechanism of action for our key assets. The candidate will gain practical experience with day-to-day challenges in pharmaceutical research and learn about spatial biology and proteomics and how such efforts play a role in drug discovery. The Co-op will participate in departmental and project team meetings to provide a broad perspective on the drug discovery or development process in the pharmaceutical industry.

Key Responsibilities

  • Perform formalin-fixed, paraffin-embedded (FFPE) tissue processing and sectioning
  • Execute high-resolution, multiplexed immunofluorescence (IF) or immunohistochemistry (IHC) staining on FFPE sections
  • Operate advanced laser microdissection systems to physically isolate selected cells or sub-cellular regions from the tissue slides
  • Leverage ultra-sensitive mass spectrometry-based proteomics for tissue profiling
  • Collaborate with team members to troubleshoot and optimize workflows
  • Participate in lab meetings and present findings

Required Education & Experience

  • Candidates must be currently pursuing a Ph.D. in Biology, Biophysics, Biochemistry, Chemical Biology or related field
  • Candidates must have completed at least two years of studies toward a PhD or equivalent degree
  • Candidates must have strong knowledge and experience in FFPE tissue sectioning and mounting on slides
  • Candidate must have basic knowledge and experience in fluorescence imaging and analysis
  • Candidates must be available to work full-time for approximately 6 months beginning in early to mid-2027

Preferred Experience & Skills

  • Proficiency in machine learning-based image analysis and in one or more programming languages (R, Python, etc.)
  • Hands-on experience with laser capture microdissection
  • Familiarity with sample preparation techniques for proteomics or other -omics analysis
  • Strong publication record and/or presentations at scientific conferences
  • Candidates should have a GPA of 3.0 or higher

Pay

The salary range for this role is $39,108 through $111,111.

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